Adjuvant Radiotherapy Delays Recurrence Following Subtotal Resection of Spinal Cord Ependymomas
— Categories: Ependymoma Research Articles Posted on February 15, 2013
This article represents a secondary analysis of existing published data of the impact of the extent of surgery and adjuvant radiation therapy in adults with spinal cord ependymoma.
The final sample consisted of 348 patients from 68 separate studies, of which 77% had a gross total resection and nearly 60% received adjuvant radiation therapy. Overall progression free survival (PFS) was prolonged in those who received adjuvant radiation therapy. However, improved overall survival (OS) was only associated with extent of surgery and having a low grade tumor.