CERN Supported Research Profiles Posterior Fossa Ependymomas

— Categories: CERN Research Articles     Posted on July 2, 2018

Of nine ependymoma molecular groups detected by DNA methylation profiling, the posterior fossa type A (PFA) is most prevalent. Researchers used DNA methylation profiling to look for further molecular heterogeneity among 675 PFA ependymomas.

Two major subgroups, posterior fossa PFA-1 and PFA-2, and nine minor subtypes were discovered.

This was a multicenter collaboration between the 2018 CERN Foundation Scientific Ependymoma Fellowship recipient, Dr. Kristian Pajtler, the German Cancer Research Center (DKFZ), St. Jude Children’s Research Hospital, the Hospital for Sick Children in Toronto, and the University of Nottingham, England.

To read the Acta Neuropathologica Article, click here.

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