Maintenance and Dysfunction Predict Recurrence in Pediatric Ependymoma

— Categories: Ependymoma Research Articles     Posted on October 25, 2008

The enzymatic subunit of telomerase (hTERT) is an important prognostic marker for paediatric ependymoma. Because of the lack of good, representative pre-clinical models for ependymoma, researchers took advantage of their large cohort of ependymoma patients, some with multiple recurrences, to investigate telomere biology in these tumours.

The cohort consisted of 133 ependymomas from 83 paediatric patients and included 31 patients with recurrences.

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